Creatinine is the end-product of creatine metabolism. The presence of creatine is primarily in muscle. The amount of creatinine is related to total skeletal muscle mass. Daily creatinine production is regular, except when there is a massive injury to muscle. In healthy individuals, the kidneys excrete creatinine, and blood levels and daily urinary excretion of creatinine fluctuate very little.
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Quentin Caswell, MSN, is an Integrative and Functional Medicine Specialist dedicated to helping patients feel their best. Board certified in advanced bioidentical hormone replacement and peptide therapy, he earned his Master of Science in Nursing from the University of Missouri (Mizzou) and opened Advanced Practice Wellness Clinic in 2011.